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Partially-deuterated oligo-DNA reduces overcrowding, enhances resolution and sensitivity and provide improved NMR constraints for structure elucidation of oligo-DNA
Uppsala University.
Uppsala University.
Uppsala University.
1998 (English)In: TETRAHEDRON, ISSN 0040-4020, Vol. 54, no 48, 14515-14528 p.Article in journal (Other scientific) Published
Abstract [en]

The usefulness of the "NMR-window III" approach (see ref. 2e) has been demonstrated through the use of the deuterio isotopomeric 12mer oligo-DNA duplex obtained from protected partially deuterated 2'((R) under bar/(S) under bar), 3', 5'((R) under bar/(S)

Place, publisher, year, edition, pages
PERGAMON-ELSEVIER SCIENCE LTD , 1998. Vol. 54, no 48, 14515-14528 p.
Keyword [en]
COUPLING-CONSTANTS; ENZYMATIC-SYNTHESIS; H-1-NMR WINDOW; HETERONUCLEAR NMR; RNA; PROTONS; OLIGONUCLEOTIDES; NUCLEOSIDES; DERIVATIVES; ASSIGNMENT
Identifiers
URN: urn:nbn:se:uu:diva-27423OAI: oai:DiVA.org:uu-27423DiVA: diva2:55318
Note
Addresses: Chattopadhyaya J, Univ Uppsala, Ctr Biomed, Dept Bioorgan Chem, Box 581, S-75123 Uppsala, Sweden. Univ Uppsala, Ctr Biomed, Dept Bioorgan Chem, S-75123 Uppsala, Sweden.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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