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THE SOLUTION STRUCTURE OF A 3'-PHENAZINIUM (PZN) TETHERED DNA-RNA DUPLEX WITH A DANGLING ADENOSINE - R(5'GAUUGAA3')-D(5'TCAATC3'-PZN)
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1994 (English)In: NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, Vol. 22, no 25, 5590-5599 p.Article in journal (Other scientific) Published
Abstract [en]

The 3'-Pzn group tethered to an oligo-DNA stabilizes a DNA-RNA hybrid duplex structure by 13 degrees C compared to the natural counterpart. This report constitutes the first full study of the conformational features of a hybrid DNA-RNA duplex, which has b

Place, publisher, year, edition, pages
OXFORD UNIV PRESS UNITED KINGDOM , 1994. Vol. 22, no 25, 5590-5599 p.
Keyword [en]
DOUBLE-HELICAL DNA; MOLECULAR MECHANICS CALCULATIONS; RELAXATION MATRIX ANALYSIS; COUPLING-CONSTANTS; COMPLEX-FORMATION; AQUEOUS-SOLUTION; HYBRID DUPLEXES; NMR; SEQUENCE; SPECTROSCOPY
Identifiers
URN: urn:nbn:se:uu:diva-27466OAI: oai:DiVA.org:uu-27466DiVA: diva2:55361
Note
Addresses: UNIV UPPSALA, CTR BIOMED, DEPT BIOORGAN CHEM, S-75123 UPPSALA, SWEDEN. RUSSIAN ACAD SCI, INST BIOORGAN CHEM, NOVOSIBIRSK 630090, RUSSIA.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-16

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