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Antimicrobial treatment to impair expansion of abdominal aortic aneurysm (AAA): a systematic review of the clinical evidence
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
2013 (English)In: Current vascular pharmacology, ISSN 1875-6212, Vol. 11, no 3, 288-292 p.Article, review/survey (Refereed) Published
Abstract [en]

Antimicrobial treatment to attenuate expansion of abdominal aortic aneurysm has been suggested, especially with the focus on Chlamydophila. In this systematic literature review only four randomized trials were identified. In two small studies there is an indication of an effect of roxithromycin. In conclusion, however, more studies are needed, and they must be properly sized based on power calculations as well as antimicrobially relevant. Such trials are on the way both in Europe and the US, the results being awaited with interest.

Place, publisher, year, edition, pages
2013. Vol. 11, no 3, 288-292 p.
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Medical and Health Sciences
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URN: urn:nbn:se:uu:diva-181767DOI: 10.2174/1570161111311030002ISI: 000318603400002PubMedID: 22724481OAI: oai:DiVA.org:uu-181767DiVA: diva2:557502
Available from: 2012-09-28 Created: 2012-09-28 Last updated: 2013-06-18Bibliographically approved

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Bergqvist, DavidBjörck, Martin

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