High levels of cathepsins B, L and S in human seminal plasma and their association with prostasomes
2012 (English)In: Andrologia, ISSN 0303-4569, E-ISSN 1439-0272, Vol. 44, no 6, 423-427 p.Article in journal (Refereed) Published
Semen is a heterogenous and complex fluid with different functions, some of them well known, others still obscure. The aim of this study was to investigate the presence of cathepsins B, S and L in human seminal plasma and their possible associations with other semen variables. Cathepsin B, L and S concentrations were measured in seminal plasma from 99 men utilising commercial ELISA kits. Seminal plasma cathepsin B was approximately 70 times higher, while the cathepsin L values were approximately 500 times higher and the cathepsin S values approximately 40 times higher in seminal plasma than in a group of serum samples. The study shows that seminal plasma contains high levels of cathepsins B, L and S. All three cathepsins were also bound to the surface of prostasomes.
Place, publisher, year, edition, pages
2012. Vol. 44, no 6, 423-427 p.
Obstetrics, Gynecology and Reproductive Medicine
IdentifiersURN: urn:nbn:se:uu:diva-182323DOI: 10.1111/j.1439-0272.2012.01299.xISI: 000310476700011PubMedID: 22571763OAI: oai:DiVA.org:uu-182323DiVA: diva2:559455