uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Pair rule gene orthologs in spider segmentation
Universität zu Köln.
Uppsala University, Disciplinary Domain of Science and Technology, Earth Sciences, Department of Earth Sciences, Palaeobiology.
Universität zu Köln.
2005 (English)In: Evolution & Development, ISSN 1520-541X, E-ISSN 1525-142X, Vol. 7, no 6, 618-628 p.Article in journal (Refereed) Published
Abstract [en]

The activation of pair rule genes is the first indication of the metameric organization of the Drosophila embryo and thus forms a key step in the segmentation process. There are two classes of pair rule genes in Drosophila: the primary pair rule genes that are directly activated by the maternal and gap genes and the secondary pair rule genes that rely on input from the primary pair rule genes. Here we analyze orthologs of Drosophila primary and secondary pair rule orthologs in the spider Cupiennius salei. The expression patterns of the spider pair rule gene orthologs can be subdivided in three groups: even-skipped and runt-1 expression is in stripes that start at the posterior end of the growth zone and their expression ends before the stripes reach the anterior end of the growth zone, while hairy and pairberry-3 stripes also start at the posterior end, but do not cease in the anterior growth zone. Stripes of odd-paired, odd-skipped-related-1, and sloppy paired are only found in the anterior portion of the growth zone. The various genes thus seem to be active during different phases of segment specification. It is notable that the spider orthologs of the Drosophila primary pair rule genes are active more posterior in the growth zone and thus during earlier phases of segment specification than most orthologs of Drosophila secondary pair rule genes, indicating that parts of the hierarchy might be conserved between flies and spiders. The spider ortholog of the Drosophila pair rule gene fushi tarazu is not expressed in the growth zone, but is expressed in a Hox-like fashion. The segmentation function of fushi tarazu thus appears to be a newly acquired role of the gene in the lineage of the mandibulate arthropods.


Place, publisher, year, edition, pages
2005. Vol. 7, no 6, 618-628 p.
National Category
URN: urn:nbn:se:uu:diva-182613DOI: 10.1111/j.1525-142X.2005.05065.xISI: 000233141300012PubMedID: 16336415OAI: oai:DiVA.org:uu-182613DiVA: diva2:560222
Symposium on Terminal Addition, Segmentation and the Evolution of Metazoan Body Plan Regionalization, San Diego, USA, 7-8 Jan 2005
Available from: 2012-10-12 Created: 2012-10-12 Last updated: 2015-05-05Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Janssen, Ralf
By organisation
In the same journal
Evolution & Development

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 136 hits
ReferencesLink to record
Permanent link

Direct link