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Induced fit on sugar binding activates ribokinase
Uppsala University.
Uppsala University.
Uppsala University.
1999 (English)In: JOURNAL OF MOLECULAR BIOLOGY, ISSN 0022-2836, Vol. 290, no 5, 1009-1018 p.Article in journal (Other academic) Published
Abstract [en]

The enzyme ribokinase phosphorylates ribose at O5* as the first step in its metabolism. The original X-ray structure of Escherichia coli ribokinase represented the ternary complex including ribose and ADP. Structures are presented here for the apo enzyme,

Place, publisher, year, edition, pages
ACADEMIC PRESS LTD , 1999. Vol. 290, no 5, 1009-1018 p.
Keyword [en]
conformational changes; induced fit; kinase; ribose; X-ray crystallography; ESCHERICHIA-COLI RIBOKINASE; MACROMOLECULAR STRUCTURES; ADENOSINE KINASE; PROTEIN; REFINEMENT; RESOLUTION; ANALOGS; PROGRAM; RIBOSE
Identifiers
URN: urn:nbn:se:uu:diva-28289OAI: oai:DiVA.org:uu-28289DiVA: diva2:56185
Note
Addresses: Mowbray SL, Swedish Univ Agr Sci, Ctr Biomed, Dept Mol Biol, Box 590, S-75124 Uppsala, Sweden. Swedish Univ Agr Sci, Ctr Biomed, Dept Mol Biol, S-75124 Uppsala, Sweden. Univ Uppsala, Dept Mol Biol, S-75105 Uppsala, Sweden.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2015-03-31

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