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Inflammatory studies on bone cement
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences. Uppsala University, Disciplinary Domain of Science and Technology, Biology, Biology Education Centre. (Materials in Medicine)
2012 (English)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Simvastatin, a cholesterol lowering drug, has the capacity to stimulate bone formation along with having anti-inflammatory effects. Incorporating simvastatin to the calcium phosphate cement would result in slow release of the drug stimulating bone formation and by preventing a local inflammation and bone resorption. The main aim is to study and examine the inflammatory response towards calcium phosphate cements in vitro and compare it with cements incorporated with simvastatin.

Place, publisher, year, edition, pages
2012. , 28 p.
Keyword [en]
Bone cements, Calcium Phosphate cements, Simvastatin, RAW 264.7 cells, Macrophages, ROS, Inflammation
National Category
Engineering and Technology
Identifiers
URN: urn:nbn:se:uu:diva-187460OAI: oai:DiVA.org:uu-187460DiVA: diva2:574794
Subject / course
Material
Educational program
Master Programme in Applied Biotechnology
Presentation
2012-11-06, B7:217 A, BMC, Uppsala, 13:15 (English)
Uppsok
Medicine
Supervisors
Examiners
Available from: 2013-06-11 Created: 2012-12-06 Last updated: 2013-06-11Bibliographically approved

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CiteExportLink to record
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Citation style
  • apa
  • ieee
  • modern-language-association
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More styles
Language
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  • en-US
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  • nn-NB
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Output format
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