Inflammatory studies on bone cement
Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Simvastatin, a cholesterol lowering drug, has the capacity to stimulate bone formation along with having anti-inflammatory effects. Incorporating simvastatin to the calcium phosphate cement would result in slow release of the drug stimulating bone formation and by preventing a local inflammation and bone resorption. The main aim is to study and examine the inflammatory response towards calcium phosphate cements in vitro and compare it with cements incorporated with simvastatin.
Place, publisher, year, edition, pages
2012. , 28 p.
Bone cements, Calcium Phosphate cements, Simvastatin, RAW 264.7 cells, Macrophages, ROS, Inflammation
Engineering and Technology
IdentifiersURN: urn:nbn:se:uu:diva-187460OAI: oai:DiVA.org:uu-187460DiVA: diva2:574794
Subject / course
Master Programme in Applied Biotechnology
2012-11-06, B7:217 A, BMC, Uppsala, 13:15 (English)