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Eczema Increases Susceptibility to PM10 in Office Indoor Environments
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Occupational and Environmental Medicine.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Occupational and Environmental Medicine.
2012 (English)In: Archives of Environmental & Occupational Health, ISSN 1933-8244, E-ISSN 2154-4700, Vol. 67, no 1, 15-21 p.Article in journal (Refereed) Published
Abstract [en]

The objective was to compare impact of indoor office environment on employees with eczema with those without eczema. Exposure was measured at 56 sites and modelled for 173 work places. Tear film stability, lysozyme in nasal lavage, immunoglobulin E (IgE), and Phadiatop were assessed, and symptoms and perceptions collected by questionnaires. Multiple regression analyses were applied, adjusted for age, gender, strain, current smoking, and respiratory infections. Those with eczema perceived temperature too high but not associated with measured temperature. They had increased lysozyme in nasal lavage associated with increased air temperature difference between 6 and 10 AM, more general and mucosal symptoms, and "dry or flushed facial skin" associated with airborne particulate matter less than 10 microns in diameter (PM10). Impact of PM10 was most pronounced among those with eczema previous 30 days. Having eczema might be an important predictor for subjective and objective responses to indoor environment.

Place, publisher, year, edition, pages
2012. Vol. 67, no 1, 15-21 p.
Keyword [en]
atopy, eczema, indoor environment, lysozyme, occupational medicine, PM10
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-172732DOI: 10.1080/19338244.2011.564236ISI: 000301728500003OAI: oai:DiVA.org:uu-172732DiVA: diva2:576672
Available from: 2012-12-13 Created: 2012-04-13 Last updated: 2017-12-06Bibliographically approved

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Wieslander, GunillaNorbäck, Dan

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