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Aspekter på läkemedelsförskrivning till äldre patienter: en analys baserad på data från Läkemedelsregistret
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences, Division of Pharmacokinetics and Drug Therapy.
2013 (Swedish)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Introduction: Aging is accompanied by an increased vulnerability to drug-related problems, and certain drugs are due to unfavorable benefit-risk balances of special concern. The Swedish National Board of Health and Welfare has developed a list of substances that are potentially inappropriate for elderly, including anticholinergic drugs, tramadol, propiomazine and long-acting benzodiazepines.

Aim: To create a foundation for interventions by illuminating aspects regarding extent and quality of drug prescribing for patients 75 years and older in Sweden, focusing on potentially inappropriate drugs, hypnotics, drugs for urinary incontinence, neuroleptics and analgesics.

Materials and Methods: Data were ordered from the Swedish Prescribed Drug Register which contains individual-based information about all out-patient prescriptions dispensed at Swedish pharmacies since July 2005. Data were processed using Microsoft Office Excel and results were analyzed using current Swedish treatment guidelines and quality indicators.

Results: During August 2011- July 2012 almost 22 % of the Swedish population aged 75 years and older were dispensed one or more potentially inappropriate drug, the most frequent being tramadol. Nearly 5 % of the elderly were introduced on hypnotics, of which the majority received zopiclone according to Swedish recommendations. Among patients introduced on drugs for urinary incontinence, treatment was often not continuous over time. Regular use of neuroleptics was seen among 4 % of patients. About 9 % were introduced on opioids, of which codeine combinations and tramadol were the most common substances.

Conclusions: Compliance to treatment guidelines is generally fairly good, but there are still potentials for improvements in prescribing for elderly patients.

Place, publisher, year, edition, pages
2013. , 55 p.
Keyword [sv]
läkemedel, äldre, läkemedelsregistret, förskrivning, prevalens, nyinsättning, potentiellt olämpliga läkemedel
National Category
Pharmaceutical Sciences
URN: urn:nbn:se:uu:diva-193383OAI: oai:DiVA.org:uu-193383DiVA: diva2:606014
External cooperation
Läkemedelsenheten Region Skåne
Subject / course
Drug Management
Available from: 2013-02-28 Created: 2013-01-31 Last updated: 2013-02-28Bibliographically approved

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