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Computational estimation of fluid mechanical benefits from a fluid deflector at the distal end of artificial vascular grafts
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Physiology.
2013 (English)In: Computers in Biology and Medicine, ISSN 0010-4825, E-ISSN 1879-0534, Vol. 43, no 2, 164-168 p.Article in journal (Refereed) Published
Abstract [en]

Intimal hyperplasia at the distal anastomosis is considered to be an important determinant for arterial and arteriovenous graft failure. The connection between unhealthy hemodynamics and intimal hyperplasia motivates the use of computational fluid dynamics modeling to search for improved graft design. However, studies on the fluid mechanical impact on intimal hyperplasia at the suture line intrusion have previously been scanty. In the present work, we focus on intimal hyperplasia at the suture line and illustrate potential benefits from the introduction of a fluid deflector to shield the suture line from unhealthily high wall shear stress.

Place, publisher, year, edition, pages
2013. Vol. 43, no 2, 164-168 p.
Keyword [en]
Artificial grafts, CFD modeling, Computational design evaluation, Vascular bypass, Wall shear stress
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-194902DOI: 10.1016/j.compbiomed.2012.11.012ISI: 000314560800011OAI: oai:DiVA.org:uu-194902DiVA: diva2:606684
Available from: 2013-02-20 Created: 2013-02-19 Last updated: 2014-03-20Bibliographically approved

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Roos, Magnus W
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