Feasibility studies. The use of NMR spectrometry as a possible substitute of or complement to several analytical tests in pharmacopoeia monographs
2012 (English)In: Pharmeuropa bio & scientific notes, ISSN 2075-2164, Vol. 2012, 87-102 p.Article in journal (Refereed) Published
NMR spectrometry has many analytical applications; for instance, the identification of known substances; the structure elucidation of unknown ones; the quantifi cation of APIs, impurities, solvent and water; kinetic studies, stereochemistry determinations, and the analyses of complex mixtures as in metabonomics. NMR spectrometry has the potential to substitute or complement existing analyses that are performed on APIs. In this work, 4 different NMR analyses were done on 2 APIs: fluvastatin sodium and benzalkonium chloride with good results.
Place, publisher, year, edition, pages
2012. Vol. 2012, 87-102 p.
Medicinal Chemistry Analytical Chemistry Pharmaceutical Sciences
IdentifiersURN: urn:nbn:se:uu:diva-196287PubMedID: 23327894OAI: oai:DiVA.org:uu-196287DiVA: diva2:609667
MEDLINE AN 2013303474(Journal; Article; (JOURNAL ARTICLE))2013-03-062013-03-062013-03-13Bibliographically approved