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Feasibility studies. The use of NMR spectrometry as a possible substitute of or complement to several analytical tests in pharmacopoeia monographs
Medical Products Agency, Uppsala, Sweden..
2012 (English)In: Pharmeuropa bio & scientific notes, ISSN 2075-2164, Vol. 2012, 87-102 p.Article in journal (Refereed) Published
Abstract [en]

NMR spectrometry has many analytical applications; for instance, the identification of known substances; the structure elucidation of unknown ones; the quantifi cation of APIs, impurities, solvent and water; kinetic studies, stereochemistry determinations, and the analyses of complex mixtures as in metabonomics. NMR spectrometry has the potential to substitute or complement existing analyses that are performed on APIs. In this work, 4 different NMR analyses were done on 2 APIs: fluvastatin sodium and benzalkonium chloride with good results.

Place, publisher, year, edition, pages
2012. Vol. 2012, 87-102 p.
National Category
Medicinal Chemistry Analytical Chemistry Pharmaceutical Sciences
URN: urn:nbn:se:uu:diva-196287PubMedID: 23327894OAI: oai:DiVA.org:uu-196287DiVA: diva2:609667

MEDLINE AN 2013303474(Journal; Article; (JOURNAL ARTICLE))

Available from: 2013-03-06 Created: 2013-03-06 Last updated: 2013-03-13Bibliographically approved

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Arvidsson, T.
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