Unfolding probes: A novel method for biomolecular detection
Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Unfolding probes is a novel detection method for biomolecules, involving an oligonucleotide probe that can be amplified and which thereby gives rise to a strong signal for individual probe - target interactions. The present project focuses on a variant of unfolding probes called 2-fold probes and on optimizing the detection efficiency of synthetic targets. Furthermore, proof of concept experiments were performed for the detection of Her2 mRNA in cells.
Place, publisher, year, edition, pages
2013. , 32 p.
Biochemistry and Molecular Biology
IdentifiersURN: urn:nbn:se:uu:diva-198831OAI: oai:DiVA.org:uu-198831DiVA: diva2:618128
Molecular Biotechnology Engineering Programme
UppsokPhysics, Chemistry, Mathematics
Nong, Rachel, PhD
Josefsson, Lars-Göran, PhD