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Small Nucleolar RNAs: Identification, Structure,and Function
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Cell and Molecular Biology, Microbiology.
2006 (English)In: Small RNAs: Analysis and Regulatory Functions / [ed] Wolfgang Nellen and Christian Hammann, Springer, 2006, 31-56 p.Chapter in book (Other academic)
Abstract [en]

The revelation in the last few years of a large number of new noncoding RNAs (ncRNAs) has revolutionized our view of how gene regulation works. This is to a large extent due to the recent advances in computational as well as experimental methodology, combined with an increasing number of sequenced genomes which have had an enormous impact on the quest for new small ncRNAs. These RNAs have a function per se and are not merely intermediates in the transfer of information from genes to proteins. Instead they have turned out to be involved in the regulation of many complex biological processes, including stress response, cell differentiation, and even in control of diseases. This chapter briefly describes some of the methods used to identify and isolate different classes of ncRNAs in the size range 50–500 nt. One of these, small nucleolar RNAs, will be discussed in detail.

Place, publisher, year, edition, pages
Springer, 2006. 31-56 p.
, Nucleic Acids and Molecular Biology, ISSN 0933-1891 ; 17
National Category
Biochemistry and Molecular Biology
URN: urn:nbn:se:uu:diva-198974DOI: 10.1007/978-3-540-28130-6_2ISBN: 9783540281306OAI: oai:DiVA.org:uu-198974DiVA: diva2:618807
Available from: 2013-04-30 Created: 2013-04-30 Last updated: 2013-11-14Bibliographically approved

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Söderbom, Fredrik
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