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Modeling of self-controlling hyperthermia based on nickel alloy ferrofluids: Proposition of new nanoparticles
Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy.
Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Materials Physics.
2013 (English)In: Journal of Magnetism and Magnetic Materials, ISSN 0304-8853, E-ISSN 1873-4766, Vol. 335, 59-63 p.Article in journal (Refereed) Published
Abstract [en]

In order to provide sufficient heat without overheating healthy tissue in magnetic fluid hyperthermia (MFH), a careful design of the magnetic properties of nanoparticles is essential. We perform a systematic calculation of magnetic properties of Ni-alloy nanoparticles. Stoner-Wohlfarth model based theories (SWMBTs) are considered and the linear response theory (LRT) is used to extract the hysteresis loop of nickel alloy nanoparticles in alternating magnetic fields. It is demonstrated that in the safe range of magnetic field intensity and frequency the LRT cannot be used for the calculation of the area in the hysteresis for magnetic fields relevant for hyperthermia. The best composition and particle size for self-controlling hyperthermia with nickel alloys is determined based on SWMBTs. It is concluded that Ni-V and Ni-Zn are good candidates for self-controlling hyperthermia.

Place, publisher, year, edition, pages
2013. Vol. 335, 59-63 p.
Keyword [en]
Hyperthermia, Self-controlling, Nickel alloy, Nanoparticle, Modeling
National Category
Engineering and Technology Physical Sciences
Identifiers
URN: urn:nbn:se:uu:diva-198888DOI: 10.1016/j.jmmm.2013.01.027ISI: 000316732000011OAI: oai:DiVA.org:uu-198888DiVA: diva2:619301
Available from: 2013-05-02 Created: 2013-04-29 Last updated: 2017-12-06Bibliographically approved

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Wolff, Max

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