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Population-based pediatric reference intervals for hematology, iron and transferrin
Department of Clinical Chemistry, County Hospital of Falun.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Biochemial structure and function.
Department of Pediatrics, County Hospital of Falun.
Department of Clinical Chemistry, County Hospital of Falun.
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2013 (English)In: Scandinavian Journal of Clinical and Laboratory Investigation, ISSN 0036-5513, Vol. 73, no 3, 253-261 p.Article in journal (Refereed) Published
Abstract [en]

Reference intervals are crucial decision-making tools aiding clinicians in differentiating between healthy and diseased populations. However, for children such values often are lacking or incomplete. Blood samples were obtained from 689 healthy children, aged 6 months to 18 years, recruited in day care centers and schools. Hematology and anemia analytes were measured on the Siemens Advia 2120 and Abbott Architect ci8200 platforms (hemoglobin, erythrocyte volume fraction [EVF], erythrocytes, mean corpuscular volume [MCV], mean corpuscular hemoglobin [MCH], mean corpuscular hemoglobin concentration [MCHC], reticulocytes, leukocytes, lymphocytes, monocytes, neutrophils, eosinophils, basophils, platelets, iron, transferrin, transferrin saturation). Age-and gender-specific pediatric reference intervals were defined by calculating 2.5th and 97.5th percentiles. The data generated is primarily applicable to a Caucasian population, but could be used by any laboratory if verified for the local patient population.

Place, publisher, year, edition, pages
2013. Vol. 73, no 3, 253-261 p.
Keyword [en]
Pediatrics, children, reference values, hematology, erythrocytes, leukocytes, blood platelets, iron, transferrin
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-200103DOI: 10.3109/00365513.2013.769625ISI: 000317486400009OAI: oai:DiVA.org:uu-200103DiVA: diva2:622701
Available from: 2013-05-23 Created: 2013-05-20 Last updated: 2014-01-08Bibliographically approved

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Ridefelt, PeterGustafsson, JanHellberg, Dan
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Biochemial structure and functionDepartment of Women's and Children's HealthCenter for Clinical Research Dalarna
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