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Endogenous compounds labeled with radionuclides of short half-life - some perspectives
Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Chemistry - BMC, Physical Organic Chemistry.
Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Chemistry - BMC, Physical Organic Chemistry.
2013 (English)In: Journal of labelled compounds & radiopharmaceuticals, ISSN 0362-4803, E-ISSN 1099-1344, Vol. 56, no 3-4, 251-262 p.Article, review/survey (Refereed) Published
Abstract [en]

In the article, the strategy and synthesis of some endogenous compounds labeled mainly with 11C are presented. There are some examples illustrating how endogenous labeled compounds in connection with positron emission tomography have unique properties to describe various biological processes, and a few examples of the use of tracers labeled with 13N and 15O are also discussed. Labeled endogenous compounds may be an important asset to describe the conditions and the status of biological systems and might therefore be a key for the future search of individualized medicine.

Place, publisher, year, edition, pages
2013. Vol. 56, no 3-4, 251-262 p.
Keyword [en]
endogenous compounds, 11C-amino acids, carbohydrates, fatty acids, ketone bodies, neurotransmitters
National Category
Natural Sciences
Identifiers
URN: urn:nbn:se:uu:diva-200863DOI: 10.1002/jlcr.3033ISI: 000318174300023OAI: oai:DiVA.org:uu-200863DiVA: diva2:625191
Available from: 2013-06-04 Created: 2013-06-04 Last updated: 2017-12-06Bibliographically approved

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Langstrom, BengtKarimi, Farhad

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