Design of symmetrical and nonsymmetrical N,N-dimethylaminopyridine derivatives as highly potent choline kinase alpha inhibitors
2013 (English)In: MedChemComm, ISSN 2040-2503, Vol. 4, no 4, 693-696 p.Article in journal (Refereed) Published
Choline kinase alpha is hyperactivated in many solid tumours and regulates malignant progression, making it a promising cancer drug target. The successful design and synthesis of novel inhibitors with high cellular activity are described.
Place, publisher, year, edition, pages
2013. Vol. 4, no 4, 693-696 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-202007DOI: 10.1039/C3MD00068KOAI: oai:DiVA.org:uu-202007DiVA: diva2:630380