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Design of symmetrical and nonsymmetrical N,N-dimethylaminopyridine derivatives as highly potent choline kinase alpha inhibitors
Imperial College London, UK.
Imperial College London, UK.
Imperial College London, UK.
Imperial College London, UK.
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2013 (English)In: MedChemComm, ISSN 2040-2503, E-ISSN 2040-2511, Vol. 4, no 4, p. 693-696Article in journal (Refereed) Published
Abstract [en]

Choline kinase alpha is hyperactivated in many solid tumours and regulates malignant progression, making it a promising cancer drug target. The successful design and synthesis of novel inhibitors with high cellular activity are described.

Place, publisher, year, edition, pages
2013. Vol. 4, no 4, p. 693-696
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Medical and Health Sciences
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URN: urn:nbn:se:uu:diva-202007DOI: 10.1039/C3MD00068KOAI: oai:DiVA.org:uu-202007DiVA, id: diva2:630380
Available from: 2013-06-18 Created: 2013-06-18 Last updated: 2017-12-06

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Publisher's full texthttp://pubs.rsc.org/en/content/articlelanding/2013/md/c3md00068k

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Åberg, Ola

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