WhichCyp: Prediction of Cytochromes P450 Inhibition
2013 (English)In: Bioinformatics, ISSN 1367-4803, E-ISSN 1460-2059, Vol. 29, no 16, 2051-2052 p.Article in journal (Refereed) Published
SUMMARY: In this work we present WhichCyp, a tool for prediction of which cytochromes P450 isoforms (among 1A2, 2C9, 2C19, 2D6 and 3A4) a given molecule is likely to inhibit. The models are built from experimental high-throughput data using support vector machines and molecular signatures.
AVAILABILITY: The WhichCyp server is freely available for use on the web at http://drug.ku.dk/whichcyp, where the WhichCyp Java program and source code is also available for download.
SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
Place, publisher, year, edition, pages
2013. Vol. 29, no 16, 2051-2052 p.
Bioinformatics and Systems Biology Bioinformatics (Computational Biology)
Research subject Bioinformatics
IdentifiersURN: urn:nbn:se:uu:diva-202123DOI: 10.1093/bioinformatics/btt325ISI: 000322337400020PubMedID: 23740742OAI: oai:DiVA.org:uu-202123DiVA: diva2:630991
FundereSSENCE - An eScience CollaborationSwedish Research Council, 2011-6129