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A severe case of Puumala hantavirus infection successfully treated with bradykinin receptor antagonist icatibant
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Anaesthesiology and Intensive Care.
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2013 (English)In: Scandinavian Journal of Infectious Diseases, ISSN 0036-5548, E-ISSN 1651-1980, Vol. 45, no 6, 494-496 p.Article in journal (Refereed) Published
Abstract [en]

A patient with severe capillary leakage syndrome caused by a Puumala hantavirus infection was treated with a single dose of icatibant, a bradykinin receptor antagonist, with a dramatic positive response. We suggest that this drug should be tested in a larger number of patients with severe hantavirus infection.

Place, publisher, year, edition, pages
2013. Vol. 45, no 6, 494-496 p.
Keyword [en]
Hantavirus, bradykinin, icatibant, capillary leakage
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-202363DOI: 10.3109/00365548.2012.755268ISI: 000318940400012OAI: oai:DiVA.org:uu-202363DiVA: diva2:631965
Available from: 2013-06-24 Created: 2013-06-24 Last updated: 2013-06-24Bibliographically approved

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Tenhunen, Jyrki
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Anaesthesiology and Intensive Care
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