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Childhood Allergies Affect Health-Related Quality of Life
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Occupational and Environmental Medicine.
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2013 (English)In: Journal of Asthma, ISSN 0277-0903, E-ISSN 1532-4303, Vol. 50, no 5, 522-528 p.Article in journal (Refereed) Published
Abstract [en]

Objective. The majority of studies investigating the effects of allergy on the children's health-related quality of life (HRQoL) address one particular allergic disease, using a disease-specific HRQoL instrument. This work aims to assess the comparative impact on HRQoL of several allergic conditions of childhood (asthma, rhinitis, eczema, and food hypersensitivity) in a large, population-based sample of Swedish 8-year-olds. Methods. Data were obtained from a Swedish birth cohort (BAMSE). At the 8-year follow-up, parents of 3236 children completed the standardized generic HRQoL instrument EQ-5D and reported on the children's symptoms of asthma, rhinitis, eczema, and food hypersensitivity. Information on allergic sensitization and lung function was available for a sub-sample of the children (n = 2370 and 2425, respectively). Results. Children in the study population had a median EQ visual analog scale (VAS) of 98 (Inter Quartile Range, IQR, 90-100). The median EQ VAS was significantly lower in children with allergic diseases. Children with asthma had the lowest median EQ VAS (90, IQR 85-98) and reported the highest prevalence of problems of "pain or discomfort" (18.2%, compared to 5.5% in children without asthma). Frequent wheezing and effort-induced wheezing were associated with high prevalence of problems of "anxiety or depression" (23.3% and 15.4%, respectively). Conclusions. Swedish 8-year-olds enjoy a good HRQoL, which though is significantly impacted by allergic diseases and particularly by asthma. Asthma symptoms are important determinants of HRQoL and symptom control should be a major goal in asthma management.

Place, publisher, year, edition, pages
2013. Vol. 50, no 5, 522-528 p.
Keyword [en]
asthma, BAMSE, eczema, EQ-5D, food hypersensitivity, rhinitis, wheezing
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-202906DOI: 10.3109/02770903.2013.789057ISI: 000319229300011OAI: oai:DiVA.org:uu-202906DiVA: diva2:634622
Available from: 2013-07-01 Created: 2013-07-01 Last updated: 2013-07-01Bibliographically approved

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