uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Osteomalaci på grund av tumörorsakad fosfatbrist: Fokus på FGF23 i fysiologi och klinik
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Renal Medicine.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Renal Medicine.
Bild- och funktionsmedicinskt centrum, Akademiska sjukhuset, Uppsala.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Metabolic Bone Diseases.
2012 (Swedish)In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 109, no 32-33, 1414-1416 p.Article in journal (Other academic) Published
Abstract [en]

Oncogenic osteomalacia is a rare syndrome caused by a small tumor, of mesenchymal origin, that produces FGF23. FGF23 is a recently described bone derived factor closely regulated by calcitriol and phosphate load. In a feedback loop it increases renal phosphate loss and decreases calcitriol activation. Unregulated production of FGF23 by a tumor causes negative phosphate balance and deficient mineralization of the skeleton, with pain and fractures as a consequence. We have used determination of a venous gradient of FGF23 as an aid in localizing FGF23 producing tumors in 10 cases. In eight cases the tumor has been removed, one patient awaits further examination and in one case it has not been possible to localize the tumor.

Place, publisher, year, edition, pages
2012. Vol. 109, no 32-33, 1414-1416 p.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-205356PubMedID: 22953430OAI: oai:DiVA.org:uu-205356DiVA: diva2:641280
Available from: 2013-08-16 Created: 2013-08-16 Last updated: 2017-12-06Bibliographically approved

Open Access in DiVA

No full text

Other links

PubMedhttp://ltarkiv.lakartidningen.se/2012/temp/pda41325.pdf

Authority records BETA

Westerberg, Per-AntonLinde, TorbjörnEklöf, HampusLjunggren, Östen

Search in DiVA

By author/editor
Westerberg, Per-AntonLinde, TorbjörnEklöf, HampusLjunggren, Östen
By organisation
Renal MedicineMetabolic Bone Diseases
In the same journal
Läkartidningen
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar

pubmed
urn-nbn

Altmetric score

pubmed
urn-nbn
Total: 453 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf