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Application of scaffolds for bone regeneration strategies: Current trends and future directions
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Orthopaedics.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Orthopaedics.
2013 (English)In: Injury, ISSN 0020-1383, E-ISSN 1879-0267, Vol. 44, S28-S33 p.Article in journal (Refereed) Published
Abstract [en]

Scaffolds are extensively used in surgery to replace missing bone and to achieve bony union and fusion. An ideal scaffold should not only maintain, induce, and restore biological functions where cells, extracellular matrix, and growth factors are needed, but also have the right properties with respect to degradation, cell binding, cellular uptake, non-immunogenicity, mechanical strength, and flexibility. Here we examine both the basic science behind the development of scaffolds and comprehensively and systematically review the clinical applications. 

Place, publisher, year, edition, pages
2013. Vol. 44, S28-S33 p.
Keyword [en]
Scaffolds, Bone regeneration, Preclinical studies, Clinical applications
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Orthopedics
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URN: urn:nbn:se:uu:diva-205351DOI: 10.1016/S0020-1383(13)70007-XISI: 000321462700006OAI: oai:DiVA.org:uu-205351DiVA: diva2:641414
Available from: 2013-08-16 Created: 2013-08-16 Last updated: 2017-12-06Bibliographically approved

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Larsson, Sune

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