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Evaluation of different methods for analysis of specific gravity of canine and feline urine
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health.
2013 (English)Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
Abstract [en]

Urine specific gravity is used for evaluation of kidney function in dogs and cats. The most commonly used method to determine urine specific gravity is the refractometer. There are refractometers specifically calibrated for feline urine.The aim of this study was to evaluate how five different types of refractometers, of which two were calibrated for feline urine, report urine specific gravity. The evaluation also included comparison of the results with two other methods; determination of dry weight and chemical analysis of urine.Patient urine samples from 31 dogs and 27 cats were used. For analysis, methods included five refractometers, drying and determination of dry weight, and chemical analysis of concentration of eight solutes in urine. A urine dipstick specific gravity method was also included in the evaluation.The refractometers reported persistently different results but comparable results to the chemical analysis. The two refractometers designed for feline urine reported similar and consistently false low values. Results from the drying were interpreted to be false high and urine dipstick analysis of specific gravity reported false low results and was considered inaccurate.The conclusion is that none of the methods included reported correct results compared to the chemical analysis; the results were either false low or false high.

Place, publisher, year, edition, pages
Keyword [en]
Specific gravity • Urine density • Refractometer • Refractive index • Cat
National Category
Clinical Laboratory Medicine
URN: urn:nbn:se:uu:diva-206539OAI: oai:DiVA.org:uu-206539DiVA: diva2:644667
Educational program
Biomedical Laboratory Science Programme
Available from: 2014-06-24 Created: 2013-09-01 Last updated: 2014-06-24Bibliographically approved

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