Autologous stem cell transplantation for enteropathy-associated T-cell lymphoma: a retrospective study by the EBMT
2013 (English)In: Blood, ISSN 0006-4971, E-ISSN 1528-0020, Vol. 121, no 13, 2529-2532 p.Article in journal (Refereed) Published
Enteropathy-associated T-cell lymphoma (EATL) is a rare subtype of peripheral T-cell lymphomas with a poor prognosis. Autologous stem cell transplantation (ASCT) was retrospectively evaluated as a consolidation or salvage strategy for EATL. The analysis included 44 patients who received ASCT for EATL between 2000 and 2010. Thirty-one patients (70%) were in first complete or partial remission at the time of the ASCT. With a median follow-up of 46 months, relapse incidence, progression-free survival, and overall survival were 39%, 54%, and 59% at 4 years, respectively, with only one relapse occurring beyond 18 months posttransplant. There was a trend for better survival in patients transplanted in first complete or partial remission at 4 years (66% vs 36%; P = .062). ASCT is feasible in selected patients with EATL and can yield durable disease control in a significant proportion of the patients.
Place, publisher, year, edition, pages
2013. Vol. 121, no 13, 2529-2532 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-206763DOI: 10.1182/blood-2012-11-466839ISI: 000321762400023OAI: oai:DiVA.org:uu-206763DiVA: diva2:645384