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ISPMD consensus on the management of premenstrual disorders
Institute for Science and Technology in Medicine, Keele University, Stoke on Trent, UK.
Academic Unit of Obstetrics and Gynaecology, University Hospital North Staffordshire, Keele University School of Medicine, Stoke on Trent, Staffordshire, UK.
Umea Neurosteroid Research Center, Department of Clinical Sciences, Norrland University Hospital, Umea, Sweden.
Department of Psychiatry, University of Tennessee Health Science Centre, Memphis, USA.
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2013 (English)In: Archives of Women's Mental Health, ISSN 1434-1816, E-ISSN 1435-1102, Vol. 16, no 4, 279-291 p.Article in journal (Refereed) Published
Abstract [en]

The second consensus meeting of the International Society for Premenstrual Disorders (ISPMD) took place in London during March 2011. The primary goal was to evaluate the published evidence and consider the expert opinions of the ISPMD members to reach a consensus on advice for the management of premenstrual disorders. Gynaecologists, psychiatrists, psychologists and pharmacologists each formally presented the evidence within their area of expertise; this was followed by an in-depth discussion leading to consensus recommendations. This article provides a comprehensive review of the outcomes from the meeting. The group discussed and agreed that careful diagnosis based on the recommendations and classification derived from the first ISPMD consensus conference is essential and should underlie the appropriate management strategy. Options for the management of premenstrual disorders fall under two broad categories, (a) those influencing central nervous activity, particularly the modulation of the neurotransmitter serotonin and (b) those that suppress ovulation. Psychotropic medication, such as selective serotonin reuptake inhibitors, probably acts by dampening the influence of sex steroids on the brain. Oral contraceptives, gonadotropin-releasing hormone agonists, danazol and estradiol all most likely function by ovulation suppression. The role of oophorectomy was also considered in this respect. Alternative therapies are also addressed, with, e.g. cognitive behavioural therapy, calcium supplements and Vitex agnus castus warranting further exploration.

Place, publisher, year, edition, pages
2013. Vol. 16, no 4, 279-291 p.
Keyword [en]
Premenstrual syndrome, Premenstrual dysphoric disorder, Variant premenstrual disorder, Core premenstrual disorder, Premenstrual exacerbation, PMS, PMDD
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-207016DOI: 10.1007/s00737-013-0346-yISI: 000322114700003OAI: oai:DiVA.org:uu-207016DiVA: diva2:647102
Available from: 2013-09-10 Created: 2013-09-09 Last updated: 2014-03-14Bibliographically approved

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Sundström Poromaa, Inger
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