Radiation doses to the cell nucleus in single cells and cells in micrometastases in targeted therapy with I-131 labeled ligands or antibodies
2000 (English)In: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, ISSN 0360-3016, Vol. 46, no 4, 1025-1036 p.Article in journal (Refereed) Published
Purpose: The aim of this study was to theoretically investigate how the radiation dose to cell nuclei depends on the subcellular position of I-131. The influence of the size of the cells and crossfire irradiation in clusters of cells was also studied. Met
Place, publisher, year, edition, pages
ELSEVIER SCIENCE INC , 2000. Vol. 46, no 4, 1025-1036 p.
microdosimetry; I-131; radioimmunotherapy; targeted radiotherapy; SPHEROIDS; RADIOIMMUNOTHERAPY; PENETRATION; BINDING; RADIOTHERAPY; ANTIGEN
IdentifiersURN: urn:nbn:se:uu:diva-36814OAI: oai:DiVA.org:uu-36814DiVA: diva2:64713
Addresses: Hartman T, Univ Uppsala, Svedberg Lab, POB 533, S-75121 Uppsala, Sweden. Univ Uppsala, Svedberg Lab, S-75121 Uppsala, Sweden. Univ Uppsala, Dept Oncol Radiol & Clin Immunol, Div Biomed Radiat Sci, S-75121 Uppsala, Sweden. Univ Uppsala, Dept Onc2008-10-172008-10-172011-01-14