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Inter- and intra-molecular migration of peptide amide hydrogens during electrospray ionization
Uppsala University, Centre for Surface Biotechnology. IONPHYSICS.
Teknisk-naturvetenskapliga vetenskapsområdet, Technology, Department of Materials Science.
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2001 (English)In: JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, ISSN 1044-0305, Vol. 12, no 4, 410-419 p.Article in journal (Refereed) Published
Abstract [en]

The isotopic exchange of amide hydrogens in proteins in solution strongly depends on the surrounding protein structure, thereby allowing structural studies of proteins by mass spectrometry. However, during electrospray ionization (ESI), gas phase processe

Place, publisher, year, edition, pages
ELSEVIER SCIENCE INC , 2001. Vol. 12, no 4, 410-419 p.
Keyword [en]
RESONANCE MASS-SPECTROMETRY; PHASE HYDROGEN/DEUTERIUM EXCHANGE; GAS-PHASE; CYTOCHROME-C; DEUTERIUM-EXCHANGE; H/D-EXCHANGE; STRUCTURAL CHARACTERIZATION; CONFORMATIONAL STABILITY; CAPTURE DISSOCIATION; IONS
Identifiers
URN: urn:nbn:se:uu:diva-37161OAI: oai:DiVA.org:uu-37161DiVA: diva2:65060
Note
Addresses: Buijs J, Univ Uppsala, Div Ion Phys, Angstrom Lab, Box 534, S-75121 Uppsala, Sweden. Univ Uppsala, Div Ion Phys, Angstrom Lab, S-75121 Uppsala, Sweden. Malardalen Univ, Dept Chem Engn, Eskilstuna, Sweden.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-13

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