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Fruit and Vegetable Consumption With Risk of Abdominal Aortic Aneurysm
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
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2013 (English)In: Circulation, ISSN 0009-7322, E-ISSN 1524-4539, Vol. 128, no 8, 795-802 p.Article in journal (Refereed) Published
Abstract [en]

Background Dietary factors affecting the risk of developing abdominal aortic aneurysm (AAA) are scarcely investigated. The aim of this study was to investigate the associations of fruit and vegetable consumption with the risk to develop AAA. Methods and Results The prospective Cohort of Swedish Men and the Swedish Mammography Cohort, consisting of 44317 men and 36 09 women, 46 to 84 years of age at the start of the 13-year follow-up (1998-2010), were used. Fruit and vegetable consumption was assessed at baseline with a 96-item food-frequency questionnaire. By linkage to the Swedish Inpatient Register and the Swedish Vascular Registry (Swedvasc), 1086 primary cases of AAA (222 ruptured) were identified. Cox proportional hazards models were used to estimate hazard ratios with 95% confidence intervals (CIs). Those in the highest quartile of fruit consumption (>2.0 servings/d), in comparison with those in the lowest quartile (<0.7 servings/d), had a 25% (95% CI, 9%-38%) lower risk of AAA, and a 43% (95% CI, 11%-64%) lower risk of ruptured AAA, specifically. Consumption of 2 fruits per day was associated with 31% (95% CI, 11%-47%) lower risk of nonruptured AAA, and 39% (95% CI, 1%-63%) lower risk of ruptured AAA, in comparison with no consumption of fruit. No association was observed between vegetable consumption and AAA risk. Conclusions We observed an inverse association between consumption of fruit, but not vegetables, and the risk of AAA, with a more pronounced association with ruptured AAA.

Place, publisher, year, edition, pages
2013. Vol. 128, no 8, 795-802 p.
Keyword [en]
aortic aneurysm, abdominal, antioxidants, diet, epidemiology, risk factors
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-208081DOI: 10.1161/CIRCULATIONAHA.112.000728ISI: 000323651700012OAI: oai:DiVA.org:uu-208081DiVA: diva2:650972
Available from: 2013-09-24 Created: 2013-09-23 Last updated: 2013-09-24Bibliographically approved

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