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Dynamic landscapes: A model of context and contingency in evolution
Pluribus Systems.
Howard Hughes Medical Institute, Univ. of Michican.
University of Vienna.
Uppsala University, Disciplinary Domain of Science and Technology, Mathematics and Computer Science, Department of Information Technology, Computer Systems. (Communication Research)
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2013 (English)In: Journal of Theoretical Biology, ISSN 0022-5193, E-ISSN 1095-8541, Vol. 334, 162-172 p.Article in journal (Refereed) Published
Abstract [en]

Although the basic mechanics of evolution have been understood since Darwin, debate continues over whether macroevolutionary phenomena are driven by the fitness structure of genotype space or by ecological interaction. In this paper we propose a simple model capturing key features of fitness-landscape and ecological models of evolution. Our model describes evolutionary dynamics in a high-dimensional, structured genotype space with interspecies interaction. We find promising qualitative similarity with the empirical facts about macroevolution, including broadly distributed extinction sizes and realistic exploration of the genotype space. The abstraction of our model permits numerous applications beyond macroevolution, including protein and RNA evolution.

Place, publisher, year, edition, pages
2013. Vol. 334, 162-172 p.
Keyword [en]
Neutral networks, Macroevolution, Ecological interaction, Fitness landscape, Percolation
National Category
Evolutionary Biology Bioinformatics (Computational Biology)
URN: urn:nbn:se:uu:diva-208349DOI: 10.1016/j.jtbi.2013.05.030ISI: 000323629500017OAI: oai:DiVA.org:uu-208349DiVA: diva2:652612
Available from: 2013-06-22 Created: 2013-09-30 Last updated: 2016-10-15

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Feeney, Laura Marie
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