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Dipyrido[3,2-a : 2 ',3 '-c]phenazine-tethered oligo-DNA: Synthesis and thermal stability of their DNA center dot DNA and DNA center dot RNA duplexes and DNA center dot DNA center dot DNA triplexes
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Bioorganic Chemistry.
1999 (English)In: HELVETICA CHIMICA ACTA, ISSN 0018-019X, Vol. 82, no 12, 2186-2200 p.Article in journal (Refereed) Published
Abstract [en]

Dipyrido[3,2-a :2',3'-c]phenazine (dppz) derivatives were conjugated to 9-mer and 18-mer DNA (ODN) at a site without nucleobase, either at the 5'- or 3'-end or at a internucleotide position, via linkers of 7, 12, or 18 atoms lengths. These dppz-linked ODN

Place, publisher, year, edition, pages
WILEY-V C H VERLAG GMBH , 1999. Vol. 82, no 12, 2186-2200 p.
Keyword [en]
PHOTOINDUCED ELECTRON-TRANSFER; HELIX-SPECIFIC LIGANDS; NUCLEOTIDE CHEMISTRY; CHEMICAL NUCLEASES; OLIGONUCLEOTIDES; AGENTS; DEOXYOLIGONUCLEOTIDES; 1;10-PHENANTHROLINE; DIPYRIDOPHENAZINE; RUTHENIUM(II)
Identifiers
URN: urn:nbn:se:uu:diva-37597OAI: oai:DiVA.org:uu-37597DiVA: diva2:65496
Note
Addresses: Chattopadhyaya J, Univ Uppsala, Biomed Ctr, Dept Bioorgan Chem, Box 581, S-75105 Uppsala, Sweden. Univ Uppsala, Biomed Ctr, Dept Bioorgan Chem, S-75105 Uppsala, Sweden.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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