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Physico-chemical properties of 5 '-polyarene tethered DNA-conjugates, and their duplexes with complementary RNA
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Bioorganic Chemistry.
1999 (English)In: NUCLEOSIDES & NUCLEOTIDES, ISSN 0732-8311, Vol. 18, no 11-12, 2785-2818 p.Article in journal (Refereed) Published
Abstract [en]

Fluorophores 1-13 when covalently linked to the 5'-terminus of 9-mer ssDNA (as in ssDNA-conjugates 16-28) enhance the stablity of the duplexes with both RNA (29) and DNA (30) targets compared to the natural counterparts, which, for the first time, demonst

Place, publisher, year, edition, pages
MARCEL DEKKER INC , 1999. Vol. 18, no 11-12, 2785-2818 p.
Keyword [en]
NUCLEIC-ACIDS; MINOR-GROOVE; ANTISENSE OLIGONUCLEOTIDES; FLUORESCENCE PROPERTIES; INTERCALATING AGENTS; THERMAL-STABILITY; HYBRID DUPLEXES; B-DNA; OLIGODEOXYNUCLEOTIDES; CLEAVAGE
Identifiers
URN: urn:nbn:se:uu:diva-37599OAI: oai:DiVA.org:uu-37599DiVA: diva2:65498
Note
Addresses: Chattopadhyaya J, Univ Uppsala, Ctr Biomed, Dept Bioorgan Chem, Box 581, S-75123 Uppsala, Sweden. Univ Uppsala, Ctr Biomed, Dept Bioorgan Chem, S-75123 Uppsala, Sweden.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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