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The synthesis of deuterionucleosides
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Bioorganic Chemistry.
2000 (English)In: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, Vol. 19, no 10-12, 1615-1656 p.Article, book review (Other scientific) Published
Abstract [en]

The synthesis of deuterionucleosides for site-specific incorporation into oligo-DNA or -RNA is herein reviewed for NMR or biological studies. The review covers the following aspects: (i) deuteration of the aglycone; (ii) single-site chemical deuteration o

Place, publisher, year, edition, pages
MARCEL DEKKER INC , 2000. Vol. 19, no 10-12, 1615-1656 p.
Keyword [en]
ACID RELATED-COMPOUNDS; NUCLEAR-MAGNETIC-RESONANCE; HYDROGEN-DEUTERIUM EXCHANGE; HIGHLY DIASTEREOSELECTIVE SYNTHESIS; DEUTERATED HYDROXYMETHYL GROUP; LASER-RAMAN SPECTROSCOPY; PROCHIRAL C-5' PROTONS; ENZYMATIC-SYNTHESIS; NMR-SPECTROSCOPY; OLIGO-DNA
Identifiers
URN: urn:nbn:se:uu:diva-37634OAI: oai:DiVA.org:uu-37634DiVA: diva2:65533
Note
Addresses: Foldesi A, Univ Uppsala, Ctr Biomed, Dept Bioorgan Chem, Box 581, S-75123 Uppsala, Sweden. Univ Uppsala, Ctr Biomed, Dept Bioorgan Chem, S-75123 Uppsala, Sweden.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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