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Synthesis of multiply labelled ribonucleosides for sequence-specific labelling of oligo-RNA
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Bioorganic Chemistry.
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2001 (English)In: JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, ISSN 0362-4803, Vol. 44, no 11, 763-783 p.Article in journal (Refereed) Published
Abstract [en]

The synthesis of ribonucleotide blocks multiply labelled with H-2, C-13 and N-15 for solid support synthesis of sequence specifically labelled RNA is described. Labels were introduced in the ribose ring ( C-13), C5 position of pyrimidine nucleobases (H-2)

Place, publisher, year, edition, pages
JOHN WILEY & SONS LTD , 2001. Vol. 44, no 11, 763-783 p.
Keyword [en]
ribonucleoside; multiple labelling; stable isotopes; H-2; C-13; N-15; oligo-RNA; TRIPLE-RESONANCE EXPERIMENTS; NUCLEAR-MAGNETIC-RESONANCE; ENZYMATIC-SYNTHESIS; HETERONUCLEAR NMR; N-15-LABELED RNA; C-13; DNA; N-15; NUCLEOSIDES; ADENOSINE
Identifiers
URN: urn:nbn:se:uu:diva-37655OAI: oai:DiVA.org:uu-37655DiVA: diva2:65554
Note
Addresses: Milecki J, Adam Mickiewicz Univ Poznan, Fac Chem, Grunwaldzka 6, PL-60780 Poznan, Poland. Adam Mickiewicz Univ Poznan, Fac Chem, PL-60780 Poznan, Poland. Univ Uppsala, Ctr Biomed, Dept Bioorgan Chem, SE-75123 Uppsala, Sweden. Polish Acad Sci, IAvailable from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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