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Synthesis of [Ru(phen)(2)dppz](2+)-tethered oligo-DNA and studies on the metallointercalation mode into the DNA duplex
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Bioorganic Chemistry.
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Bioorganic Chemistry.
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Bioorganic Chemistry.
2001 (English)In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, Vol. 123, no 15, 3551-3562 p.Article in journal (Refereed) Published
Abstract [en]

To explore the binding properties of [Ru(phen)(2)dppz](2+) complex (phen = l,10-phenanthroline, dppz = dipyrido[3,2-a:2',3'-c]phenazine) in a sequence-specific manner in DNA duplex. it was tethered through the dppz ligand to a central position as well as

Place, publisher, year, edition, pages
2001. Vol. 123, no 15, 3551-3562 p.
Keyword [en]
MOLECULAR LIGHT SWITCH; SOLID-PHASE SYNTHESIS; CIRCULAR-DICHROISM; METAL-COMPLEXES; POLYPYRIDYLRUTHENIUM(II) COMPLEXES; DIPYRIDOPHENAZINE COMPLEXES; THERMAL-STABILITY; ELECTRON-TRANSFER; OLIGONUCLEOTIDES; BINDING
Identifiers
URN: urn:nbn:se:uu:diva-37660OAI: oai:DiVA.org:uu-37660DiVA: diva2:65559
Note
Addresses: Chattopadhyaya J, Univ Uppsala, Dept Bioorgan Chem, Biomed Ctr, Box 581, Uppsala, Sweden. Univ Uppsala, Dept Bioorgan Chem, Biomed Ctr, Uppsala, Sweden.Available from: 2005-06-07 Created: 2005-06-07 Last updated: 2011-01-14

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Ossipov, DChattopadhyaya, J

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