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Inorganic nanomaterials as delivery systems for proteins, peptides, DNA, and siRNA
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmacy.
2013 (English)In: Current Opinion in Colloid & Interface Science, ISSN 1359-0294, E-ISSN 1879-0399, Vol. 18, no 5, 468-480 p.Article, review/survey (Refereed) Published
Abstract [en]

With large current interest in nanomedicine, there has been rapid progress during the last couple of years in the understanding of opportunities offered by advanced materials in diagnostics, drug delivery, functional biomaterials, and biosensors, as well as combinations of these, e.g., theranostics. In the present overview, focus is placed on drug delivery aspects of inorganic nanomaterials, notably as carriers for proteins, peptides, DNA, and siRNA. Throughout, an attempt is made to illustrate how structure and interactions affect loading and release of such biomacromolecular drugs in various inorganic delivery systems, and how this translates into functional advantages.

Place, publisher, year, edition, pages
2013. Vol. 18, no 5, 468-480 p.
Keyword [en]
Delivery, DNA, Inorganic, Nanomaterial, Peptide, Protein, siRNA
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-209223DOI: 10.1016/j.cocis.2013.06.002ISI: 000324356400010OAI: oai:DiVA.org:uu-209223DiVA: diva2:656392
Available from: 2013-10-15 Created: 2013-10-15 Last updated: 2017-12-06Bibliographically approved

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Malmsten, Martin

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