Role of conserved local motifs in folding and stability of hGSTP1-1
2001 (English)In: CHEMICO-BIOLOGICAL INTERACTIONS, ISSN 0009-2797, Vol. 133, no 1-3, 17-18 p.Article in journal (Refereed) Published
We investigated, by site directed mutagenesis, the role played by a conserved N-capping box and hydrophobic staple motif in the folding and stability of human GSTPl-1. The corresponding mutants, I149A, S150A, D153A and Y154A, in which these motifs have be
Place, publisher, year, edition, pages
ELSEVIER SCI IRELAND LTD , 2001. Vol. 133, no 1-3, 17-18 p.
folding; hGSTP1-1; N-capping box; hydrophobic staple motif; TRANSFERASE P1-1
IdentifiersURN: urn:nbn:se:uu:diva-38011OAI: oai:DiVA.org:uu-38011DiVA: diva2:65910
Addresses: Aceto A, Univ G DAnnunzio, Dipartimento Sci Biomed, Via Vestini 31, I-66100 Chieti, Italy. Univ G DAnnunzio, Dipartimento Sci Biomed, I-66100 Chieti, Italy. Uppsala Univ, Biomed Ctr, Dept Biochem, SE-75123 Uppsala, Sweden.2008-10-172008-10-172011-01-14