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Solid phase synthesis of partially protected tocinoic acid: Optimization with respect to resin and protecting groups
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Chemistry, Department of Biochemistry.
2001 (English)In: JOURNAL OF PEPTIDE SCIENCE, ISSN 1075-2617, Vol. 7, no 7, 349-357 p.Article in journal (Refereed) Published
Abstract [en]

A few solid phase and solution approaches of good repute were applied in parallel with the aim to provide optimized routes to Boc- and Fmoc-tocinoic acid (3a and 3c) and the corresponding Tyr(Bu-t) derivatives (3b and 3d). Boc-tocinoic acid is known to co

Place, publisher, year, edition, pages
JOHN WILEY & SONS LTD , 2001. Vol. 7, no 7, 349-357 p.
Keyword [en]
optimized synthesis; oxytocin segment; solid phase synthesis; synthetic methodology; tocinoic acid; AMINO-ACIDS; PEPTIDE-SYNTHESIS; 2-CHLOROTRITYL RESIN; ANALOGS; COMBINATION; FRAGMENTS; OXYTOCIN
Identifiers
URN: urn:nbn:se:uu:diva-38017OAI: oai:DiVA.org:uu-38017DiVA: diva2:65916
Note
Addresses: Hlavacek J, Acad Sci Czech Republ, Inst Organ Chem & Biochem, Flemingovo Nam 2, CR-16610 Prague 6, Czech Republic. Acad Sci Czech Republ, Inst Organ Chem & Biochem, CR-16610 Prague 6, Czech Republic. Univ Uppsala, Ctr Biomed, Dept Biochem, S-75Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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