Solid phase synthesis of partially protected tocinoic acid: Optimization with respect to resin and protecting groups
2001 (English)In: JOURNAL OF PEPTIDE SCIENCE, ISSN 1075-2617, Vol. 7, no 7, 349-357 p.Article in journal (Refereed) Published
A few solid phase and solution approaches of good repute were applied in parallel with the aim to provide optimized routes to Boc- and Fmoc-tocinoic acid (3a and 3c) and the corresponding Tyr(Bu-t) derivatives (3b and 3d). Boc-tocinoic acid is known to co
Place, publisher, year, edition, pages
JOHN WILEY & SONS LTD , 2001. Vol. 7, no 7, 349-357 p.
optimized synthesis; oxytocin segment; solid phase synthesis; synthetic methodology; tocinoic acid; AMINO-ACIDS; PEPTIDE-SYNTHESIS; 2-CHLOROTRITYL RESIN; ANALOGS; COMBINATION; FRAGMENTS; OXYTOCIN
IdentifiersURN: urn:nbn:se:uu:diva-38017OAI: oai:DiVA.org:uu-38017DiVA: diva2:65916
Addresses: Hlavacek J, Acad Sci Czech Republ, Inst Organ Chem & Biochem, Flemingovo Nam 2, CR-16610 Prague 6, Czech Republic. Acad Sci Czech Republ, Inst Organ Chem & Biochem, CR-16610 Prague 6, Czech Republic. Univ Uppsala, Ctr Biomed, Dept Biochem, S-752008-10-172008-10-172011-01-14