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Microsatellite mutations in the germline: implications for evolutionary inference
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
2000 (English)In: TRENDS IN GENETICS, Vol. 16, no 12, 551-558 p.Article, book review (Other scientific) Published
Abstract [en]

Microsatellite DNA sequences mutate at rates several orders of magnitude higher than that of the bulk of DNA. Such high rates mean that spontaneous mutations that form new-length variants can realistically be seen in pedigree analysis. Data on observed mu

Place, publisher, year, edition, pages
ELSEVIER SCIENCE LONDON , 2000. Vol. 16, no 12, 551-558 p.
Keyword [en]
SIMPLE SEQUENCE DNA; GC CONTENT; SACCHAROMYCES-CEREVISIAE; DROSOPHILA-MELANOGASTER; FLANKING SEQUENCES; TANDEM REPEAT; LOCI; INSTABILITY; RATES; TRINUCLEOTIDE
Identifiers
URN: urn:nbn:se:uu:diva-38078OAI: oai:DiVA.org:uu-38078DiVA: diva2:65977
Note
Addresses: Ellegren H, Uppsala Univ, Evolutionary Biol Ctr, Dept Evolutionary Biol, Norbyvagen 18D, SE-75236 Uppsala, Sweden. Uppsala Univ, Evolutionary Biol Ctr, Dept Evolutionary Biol, SE-75236 Uppsala, Sweden.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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