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Molecular clocks reduce plasmid loss rates: The R1 case
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Cell and Molecular Biology.
2000 (English)In: JOURNAL OF MOLECULAR BIOLOGY, ISSN 0022-2836, Vol. 297, no 1, 179-192 p.Article in journal (Refereed) Published
Abstract [en]

Plasmids control their replication so that the replication frequency per plasmid copy responds to the number of plasmid copies per cell. High sensitivity amplification in replication response to copy number deviations generally reduces variation in copy n

Place, publisher, year, edition, pages
ACADEMIC PRESS LTD , 2000. Vol. 297, no 1, 179-192 p.
Keyword [en]
R1; plasmid; regulation; stochastic; kinetics; COPY-NUMBER CONTROL; ESCHERICHIA-COLI; ANTISENSE RNA; BACTERIAL PLASMIDS; MATHEMATICAL-MODEL; REPLICATION; STABILITY; GROWTH; INSTABILITY; INHIBITION
Identifiers
URN: urn:nbn:se:uu:diva-38151OAI: oai:DiVA.org:uu-38151DiVA: diva2:66050
Note
Addresses: Ehrenberg M, Ctr Biomed, Dept Cell & Mol Biol, Box 596, SE-75124 Uppsala, Sweden. Ctr Biomed, Dept Cell & Mol Biol, SE-75124 Uppsala, Sweden.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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