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On the evolution of redundancy in genetic codes
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
2001 (English)In: JOURNAL OF MOLECULAR EVOLUTION, ISSN 0022-2844, Vol. 53, no 4-5, 269-281 p.Article in journal (Refereed) Published
Abstract [en]

We simulate a deterministic population genetic model for the coevolution of genetic codes and protein-coding genes. We use very simple assumptions about translation, mutation, and protein fitness to calculate mutation-selection equilibria of codon frequen

Place, publisher, year, edition, pages
SPRINGER-VERLAG , 2001. Vol. 53, no 4-5, 269-281 p.
Keyword [en]
evolution; origin; code-message coevolution; redundancy; amino acid; wobble; mutation-selection balance; codon usage; TRANSFER-RNA; AMINO-ACIDS; ORIGIN
Identifiers
URN: urn:nbn:se:uu:diva-38215OAI: oai:DiVA.org:uu-38215DiVA: diva2:66114
Note
Addresses: Ardell DH, Uppsala Univ, Dept Mol Evolut, Evolutionary Biol Ctr, Norbyvagen 18C, S-75236 Uppsala, Sweden. Uppsala Univ, Dept Mol Evolut, Evolutionary Biol Ctr, S-75236 Uppsala, Sweden. Stanford Univ, Dept Biol Sci, Stanford, CA 94305 USA.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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