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Metal ion cooperativity in ribozyme cleavage of RNA
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Cell and Molecular Biology.
2001 (English)In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, Vol. 98, no 23, 12943-12947 p.Article in journal (Refereed) Published
Abstract [en]

Combinations of chemical and genetic approaches were used to study the function of divalent metal ions in cleavage of RNA by the ribozyme RNase P RNA. We show that different divalent metal ions have differential effects on cleavage site recognition and re

Place, publisher, year, edition, pages
2001. Vol. 98, no 23, 12943-12947 p.
Keyword [en]
RNase P; divalent metal ions; tRNA precursors; tRNA processing; ESCHERICHIA-COLI; P-RNA; CATALYTIC SUBUNIT; RIBONUCLEASE-P; M1 RNA; BACILLUS-SUBTILIS; SITE SELECTION; MAGNESIUM-IONS; BINDING; REQUIREMENTS
Identifiers
URN: urn:nbn:se:uu:diva-38228OAI: oai:DiVA.org:uu-38228DiVA: diva2:66127
Note
Addresses: Kirsebom LA, Univ Uppsala, Ctr Biomed, Dept Cell & Mol Biol, Box 596, SE-75124 Uppsala, Sweden. Univ Uppsala, Ctr Biomed, Dept Cell & Mol Biol, SE-75124 Uppsala, Sweden.Available from: 2008-06-18 Created: 2008-06-18 Last updated: 2011-01-14

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