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Introduction of an RNA stability element at the 5 '-end of an antisense RNA cassette increases the inhibition of target RNA translation
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Cell and Molecular Biology.
2001 (English)In: ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, ISSN 1087-2906, Vol. 11, no 1, 29-40 p.Article in journal (Refereed) Published
Abstract [en]

This communication describes improvement strategies used on a previously described two-unit antisense RNA cassette system. This cassette system encodes RNA with noncontiguous regions of complementarity to a bacterial target RNA, lad mRNA, One of the units

Place, publisher, year, edition, pages
MARY ANN LIEBERT INC PUBL , 2001. Vol. 11, no 1, 29-40 p.
Keyword [en]
BULGED-OUT NUCLEOTIDES; PLASMID R1; MESSENGER-RNA; ESCHERICHIA-COLI; KISSING COMPLEX; 4-WAY JUNCTION; REPLICATION; BINDING; COPA; DUPLEX
Identifiers
URN: urn:nbn:se:uu:diva-38245OAI: oai:DiVA.org:uu-38245DiVA: diva2:66144
Note
Addresses: Wagner EGH, Uppsala Univ, Dept Microbiol, Inst Mol & Cell Biol, Husargatan 3, S-75124 Uppsala, Sweden. Uppsala Univ, Dept Microbiol, Inst Mol & Cell Biol, S-75124 Uppsala, Sweden.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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