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A fast and reliable approach to cell nuclei segmentation in PAP stained cervical smears
(CDAC Thiruvananthapuram)
(RCC Thiruvananthapuram)
Uppsala University, Disciplinary Domain of Science and Technology, Mathematics and Computer Science, Department of Information Technology, Division of Visual Information and Interaction. Uppsala University, Disciplinary Domain of Science and Technology, Mathematics and Computer Science, Department of Information Technology, Computerized Image Analysis and Human-Computer Interaction. (Centre for Image Analysis)
(CDAC Thiruvananthapuram)
2013 (English)In: CSI Transactions on ICT, ISSN 2277-9078Article in journal (Refereed) Published
Abstract [en]

Fast and reliable segmentation of cervical cellnuclei is one of the crucial steps of an automated screeningsystem that aims early detection of cervical cancer. In thispaper, we propose an edge based approach using custom-ized Laplacian of Gaussian (LoG) filter to segment freelying cell nuclei in bright-field microscope images of Papsmear. The LoG is generally employed as a second orderedge detector in image processing. The images may havethe challenges of inconsistent staining, overlapping andfolded cells. Experimenting proposed method over all typesof cervical images including sufficient number of highgrade lesions of cervical cancer shows that our methodperforms well for stain varied images containing focusednuclei.

Place, publisher, year, edition, pages
Springer India , 2013.
National Category
Signal Processing
Identifiers
URN: urn:nbn:se:uu:diva-210422DOI: 10.1007/s40012-013-0028-yOAI: oai:DiVA.org:uu-210422DiVA: diva2:662594
Available from: 2013-11-07 Created: 2013-11-07 Last updated: 2013-12-04Bibliographically approved

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Publisher's full texthttp://dx.doi.org/10.1007/s40012-013-0028-y

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Malm, Patrik

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