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The change of haemoglobin during blood donation, and an assessment of a photometrical method for non-invasive haemoglobin analysis
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health.
2013 (Swedish)Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
Abstract [en]

In Sweden, lowest acceptable haemoglobin levels in blood donators are 125g/L for women and 135g/L for men for a test sample taken in the beginning of the blood donation. Levels, which are 10g/L lower, are accepted if the sample is taken after the blood donation. Earlier studies show that the haemoglobin level decreases for a person that is lying down.

The two aims of this study were to examine how much the haemoglobin levels change during blood donation and to examine if the photometrical instrument Pronto-7TM shows equivalent results to that of the established method Cell-Dyn Sapphire.

In the study, 120 blood donors participated. Blood samples were taken in the beginning and in the end of the donation. Analyses by Pronto-7TM were done before and after the donation.

The haemoglobin level decreased significantly during the blood donation. The difference was in mean value 5,9g/L according to Cell-Dyn Sapphire. The decrease was significantly less than 10g/L. The Pronto-7TM gave levels that were 1,6g/L higher than Cell-Dyn Sapphire in mean and the standard deviation was higher for Pronto-7TM than for Cell-Dyn Sapphire.

In conclusion, the decrease of the haemoglobin levels was significantly less than the expected difference 10g/L. Pronto-7TM gives results that differs a little from the results of the established method.

Place, publisher, year, edition, pages
2013. , 19 p.
Keyword [en]
Blood donor deferral, Haemoglobin screening of blood donors, Cell-Dyn Sapphire, Pronto-7TM, Point-of-care testing
National Category
Biomedical Laboratory Science/Technology
URN: urn:nbn:se:uu:diva-210904OAI: oai:DiVA.org:uu-210904DiVA: diva2:664691
Educational program
Biomedicinska analytikerprogrammet
Available from: 2013-12-03 Created: 2013-11-15 Last updated: 2013-12-03Bibliographically approved

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