Synergetic inactivation of Staphylococcus epidermidis and Streptococcus mutans in a TiO2/H 2O2/UV system
2013 (English)In: Biomatter, ISSN 2159-2535, Vol. 3, no 4, e26727- p.Article in journal (Refereed) Published
TiO 2 photocatalysis can be used to kill surface adherent bacteria on biomaterials, and is particularly interesting for use with percutaneous implants and devices. Its efficiency and safety, however, depend on the activation energy required. This in vitro study investigates synergetic effects against the clinically relevant strains S. epidermidis and S. mutans when combining photocatalytic surfaces with H 2O 2. After 20 min exposure to 0.1 wt% H 2O 2 and UV light on TiO 2 surfaces, viabilities of S. epidermidis and S. mutans were reduced by 99.7% and 98.9%, respectively. Without H 2O 2 the corresponding viability reduction was 86% for S. epidermidis and 65% for S. mutans. This study indicates that low concentrations of H 2O 2 can enhance the efficiency of photocatalytic TiO 2 surfaces, which could potentially improve current techniques used for decontamination and debridement of TiO 2 coated biomedical implants and devices.
Place, publisher, year, edition, pages
2013. Vol. 3, no 4, e26727- p.
antibacterial, photocatalysis, photolysis, synergy, titanium dioxide, hydrogen peroxide, UV light
Biomaterials Science Engineering and Technology
Research subject Engineering Science with specialization in Nanotechnology and Functional Materials; Engineering Science with specialization in Materials Science
IdentifiersURN: urn:nbn:se:uu:diva-211547DOI: 10.4161/biom.26727PubMedID: 24135830OAI: oai:DiVA.org:uu-211547DiVA: diva2:667452
FunderSwedish Foundation for Strategic Research