uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Priors for X-ray in-line phase tomography of heterogeneous objects
Show others and affiliations
2014 (English)In: Philosophical Transactions. Series A: Mathematical, physical, and engineering science, ISSN 1364-503X, Vol. 372, no 2010, 20130129:1-9 p.Article in journal (Refereed) Published
Abstract [en]

We present a new prior for phase retrieval from X-ray Fresnel diffraction patterns. Fresnel diffraction patterns are achieved by letting a highly coherent X-ray beam propagate in free space after interaction with an object. Previously, either homogeneous or multi-material object assumptions have been used. The advantage of the homogeneous object assumption is that the prior can be introduced in the Radon domain. Heterogeneous object priors, on the other hand, have to be applied in the object domain. Here, we let the relationship between attenuation and refractive index vary as a function of the measured attenuation index. The method is evaluated using images acquired at beamline ID19 (ESRF, Grenoble, France) of a phantom where the prior is calculated by linear interpolation and of a healing bone obtained from a rat osteotomy model. It is shown that the ratio between attenuation and refractive index in bone for different levels of mineralization follows a power law. Reconstruction was performed using the mixed approach but is compatible with other, more advanced models. We achieve more precise reconstructions than previously reported in literature. We believe that the proposed method will find application in biomedical imaging problems where the object is strongly heterogeneous, such as bone healing and biomaterials engineering.

Place, publisher, year, edition, pages
2014. Vol. 372, no 2010, 20130129:1-9 p.
National Category
Medical Image Processing
URN: urn:nbn:se:uu:diva-212565DOI: 10.1098/rsta.2013.0129ISI: 000332379600014OAI: oai:DiVA.org:uu-212565DiVA: diva2:678339
Available from: 2014-01-27 Created: 2013-12-11 Last updated: 2014-04-16Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Pacureanu, Alexandra
By organisation
Division of Visual Information and InteractionComputerized Image Analysis and Human-Computer InteractionScience for Life Laboratory, SciLifeLab
In the same journal
Philosophical Transactions. Series A: Mathematical, physical, and engineering science
Medical Image Processing

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 227 hits
ReferencesLink to record
Permanent link

Direct link