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Modeling and Simulation Workbench for NONMEM: Tutorial on Pirana, PsN, and Xpose
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences. (Farmakometri)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences. (Farmakometri)
2013 (English)In: CPT: pharmacometrics & systems pharmacology, ISSN 2163-8306, Vol. 2, e50- p.Article in journal (Refereed) Published
Abstract [en]

Several software tools are available that facilitate the use of the NONMEM software and extend its functionality. This tutorial shows how three commonly used and freely available tools, Pirana, PsN, and Xpose, form a tightly integrated workbench for modeling and simulation with NONMEM. During the tutorial, we provide some guidance on what diagnostics we consider most useful in pharmacokinetic model development and how to construct them using these tools.

Place, publisher, year, edition, pages
2013. Vol. 2, e50- p.
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Medical and Health Sciences
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URN: urn:nbn:se:uu:diva-213000DOI: 10.1038/psp.2013.24PubMedID: 23836189OAI: oai:DiVA.org:uu-213000DiVA: diva2:680153
Available from: 2013-12-17 Created: 2013-12-17 Last updated: 2013-12-18Bibliographically approved

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Keizer, Ron JHooker, Andrew C

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