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Serum antichlamydial antibodies and tubal factor infertility
Alzaiem Alazhari University.
University of Khartoum.
Ribat University Hospital. (Autoimmunity)
2010 (English)In: Khartoum Medical Journal, ISSN 1858-5345, Vol. 03, no 02, 425-432 p.Article in journal (Refereed) [Artistic work] Published
Abstract [en]

Objective:

A hospital based prospective study was conducted at the Minimal Access Gynaecology Surgery (MAGS) unit at Omdurman Maternity Hospital from October 2008 December 2009 to look into serum antichlamydial antibodies and correlate the results to tubal pathology.

Method:

Sera of 175 subfertile women who all underwent a laparoscopy with tubal testing to assess the grade of tubal pathology, were tested for the presence of immunoglobulin Iggy& IgM antibodies for Chlamydia trachomatis using ELISA as well as C-reactive protein (CRP).

Results:

IgG, IgM and CRP, all serological markers of persistent infection were significantly more relevant in women with tubal pathology as compared to those without tubal pathology. The predictive value of the currently used screening test for tubal pathology I (g) G could be significantly improved by adding CRP test.

Conclusion:

Chlamydia trachomatis infection must be recognized as an important risk factor for infertility in Sudanese women. Further studies are needed to obtain more epidemiologic data about the spread of Chlamydia trachomatis among adolescent and young Sudanese women and to guide effective prevention and intervention measures including screening for Chlamydia trachomatis with specific methods and early treatment can avoid the severe squeals of this disease.

Place, publisher, year, edition, pages
2010. Vol. 03, no 02, 425-432 p.
National Category
Medical and Health Sciences
Research subject
Clinical Immunology
Identifiers
URN: urn:nbn:se:uu:diva-213134OAI: oai:DiVA.org:uu-213134DiVA: diva2:680758
Available from: 2013-12-18 Created: 2013-12-18 Last updated: 2013-12-19Bibliographically approved

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Elshafie, Amir Ibrahim

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