Prognostic implications of changes in cardiac troponin I levels in patients with non-ST elevation acute coronary syndrome
2013 (English)In: Biomarkers, ISSN 1354-750X, Vol. 18, no 8, 668-672 p.Article in journal (Refereed) Published
Objective: Information is limited on the prognostic implications of cardiac troponin I (cTnI) changes during the first days of non-ST elevation acute coronary syndrome (NSTE-ACS). Methods: High-sensitivity cTnI levels were measured at study inclusion and after 48 h in 1615 conservatively managed NSTE-ACS patients from the Global Use of Strategies To Open Occluded Coronary Arteries (GUSTO) IV trial. Results: Patients with moderately increased cTnI levels and without a relevant decrease over time had a significantly raised mortality at 30 days and 1 year. No relevant associations between cTnI changes and recurrent myocardial infarction were seen. Conclusion: The cTnI change is predictive for subsequent mortality in selected conservatively managed NSTE-ACS patients.
Place, publisher, year, edition, pages
2013. Vol. 18, no 8, 668-672 p.
Acute coronary syndrome, cardiac troponin I, cardiovascular events, risk prediction
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-213458DOI: 10.3109/1354750X.2013.843023ISI: 000327504100005OAI: oai:DiVA.org:uu-213458DiVA: diva2:682717