Cell-laden Microengineered and Mechanically Tunable Hybrid Hydrogels of Gelatin and Graphene Oxide
2013 (English)In: Advanced Materials, ISSN 0935-9648, E-ISSN 1521-4095, Vol. 25, no 44, 6385-6391 p.Article in journal (Refereed) Published
Incorporating graphene oxide inside GelMA hydrogels enhances their mechanical properties and reduces UV-induced cell damage while preserving their favorable characteristics for 3D cell encapsulation. NIH-3T3 fibroblasts encapsulated in GO-GelMA microgels demonstrate excellent cellular viability, proliferation, spreading, and alignment. GO reinforcement combined with a multi-stacking approach offers a facile engineering strategy for the construction of complex artificial tissues.
Place, publisher, year, edition, pages
2013. Vol. 25, no 44, 6385-6391 p.
graphene, microgels, tunable stiffness, tissue engineering, multilayer constructs
IdentifiersURN: urn:nbn:se:uu:diva-213932DOI: 10.1002/adma.201301082ISI: 000327692500006OAI: oai:DiVA.org:uu-213932DiVA: diva2:683631